Publicaciones Google Scholar de
1980 a
2024
| Título |
Fuente |
Fecha |
| A new fluorescent probe for the visualization of progerin |
Elsevier , 2024 |
2024 |
| eSTEM-Estudio para el avance en la diversidad e inclusión de estudiantes embarazadas en grados experimentales |
|
2024 |
| A new fluorescent probe for the visualization of progerin |
Bioorganic Chemistry 142, 106967 , 2024 |
2024 |
| Estudio de nuevas metodologías docentes que faciliten la conciliación estudiantil-familiar en grados experimentales |
Libro de actas del I Congreso de Innovación Docente de las Universidades … , 2024 |
2024 |
| New Pharmacological Approaches for Rare Diseases |
International Journal of Molecular Sciences 24 (8), 7275 , 2023 |
2023 |
| A new fluorescent probe for the visualization of progerin |
Elsevier , 2023 |
2023 |
| Operaciones básicas de laboratorio en el contexto de los objetivos de desarrollo sostenible (ODS) |
|
2023 |
| Discovery of V-0219: a small-molecule positive allosteric modulator of the glucagon-like peptide-1 receptor toward oral treatment for “diabesity” |
Journal of medicinal chemistry 65 (7), 5449-5461 , 2022 |
2022 |
| New Trends in Aging Drug Discovery |
MDPI , 2022 |
2022 |
| New trends in aging drug discovery |
Biomedicines 10 (8), 2006 , 2022 |
2022 |
| Novel Antagonist of the Type 2 Lysophosphatidic Acid Receptor (LPA 2 ), UCM-14216, Ameliorates Spinal Cord Injury in Mice |
Journal of Medicinal Chemistry 65 (16), 10956-10974 , 2022 |
2022 |
| Small-molecule therapeutic perspectives for the treatment of progeria |
International journal of molecular sciences 22 (13), 7190 , 2021 |
2021 |
| Targeting the FtsZ allosteric binding site with a novel fluorescence polarization screen, cytological and structural approaches for antibacterial discovery |
Journal of Medicinal Chemistry 64 (9), 5730-5745 , 2021 |
2021 |
| Colapso de dos endocanabinoides (AEA y PEA) en sangre en los grandes repetidores: hallazgos disruptivos en un estudio piloto |
Psicosomàtica y Psiquiatría , 2021 |
2021 |
| Chemistry for the identification of therapeutic targets: recent advances and future directions |
European Journal of Organic Chemistry 2021 (9), 1307-1320 , 2021 |
2021 |
| Isoprenylcysteine carboxylmethyltransferase-based therapy for Hutchinson–Gilford progeria syndrome |
ACS Central Science 7 (8), 1300-1310 , 2021 |
2021 |
| Serum endocannabinoid levels in suicide attempters: a pilot study |
European Neuropsychopharmacology 40, 52-60 , 2020 |
2020 |
| Blocking Ras inhibition as an antitumor strategy |
Seminars in Cancer Biology 54, 91-100 , 2019 |
2019 |
| Astroglial monoacylglycerol lipase controls mutant huntingtin-induced damage of striatal neurons |
Neuropharmacology 150, 134-144 , 2019 |
2019 |
| PF224 NOVEL ICMT INHIBITOR AS POTENTIAL TREATMENT OF RAS-DRIVEN ACUTE MYELOID LEUKEMIA |
HemaSphere 3 (S1), 64-65 , 2019 |
2019 |
| A potent isoprenylcysteine carboxylmethyltransferase (ICMT) inhibitor improves survival in Ras-driven acute myeloid leukemia |
Journal of Medicinal Chemistry 62 (13), 6035-6046 , 2019 |
2019 |
| A Novel Agonist of the Type 1 Lysophosphatidic Acid Receptor (LPA 1 ), UCM-05194, Shows Efficacy in Neuropathic Pain Amelioration |
Journal of medicinal chemistry 63 (5), 2372-2390 , 2019 |
2019 |
| A NEW RAS METHYLTRANSFERASE INHIBITOR (ICMT) AS A POTENTIAL TREATMENT AGAINST RAS MUTATED AML |
HAEMATOLOGICA 104, 142-142 , 2019 |
2019 |
| Unique pharmacological properties of serotoninergic G-protein coupled receptors from cestodes |
PLoS neglected tropical diseases 12 (2), e0006267 , 2018 |
2018 |
| 2‐AG limits Theiler's virus induced acute neuroinflammation by modulating microglia and promoting MDSCs |
Glia 66 (7), 1447-1463 , 2018 |
2018 |
| SMARTeaching: Uso de dispositivos móviles en el aula y eficacia de las clases presenciales |
|
2018 |
| Monoacylglycerol lipase (MAGL) as a promising therapeutic target |
Biochemical pharmacology 157, 18-32 , 2018 |
2018 |
| New phenylethanoid glycosides from Cistanche phelypaea and their activity as inhibitors of monoacylglycerol lipase (MAGL) |
Planta Medica 84 (09/10), 710-715 , 2018 |
2018 |
| Reversible Modulation of the Endocannabinoid System as an Anti-HIV-1 Prevention Strategy |
AIDS RESEARCH AND HUMAN RETROVIRUSES 34, 356-356 , 2018 |
2018 |
| Development of a Fluorescent Bodipy Probe for Visualization of the Serotonin 5-HT 1A Receptor in Native Cells of the Immune System |
Bioconjugate Chemistry 29 (6), 2021-2027 , 2018 |
2018 |
| Deregulation of the endocannabinoid system and therapeutic potential of ABHD6 blockade in the cuprizone model of demyelination |
Biochemical pharmacology 157, 189-201 , 2018 |
2018 |
| A Fluorescent Probe to Unravel Functional Features of Cannabinoid Receptor CB 1 in Human Blood and Tonsil Immune System Cells |
Bioconjugate chemistry 29 (2), 382-389 , 2018 |
2018 |
| Peltatoside isolated from Annona crassiflora induces peripheral antinociception by activation of the cannabinoid system |
Planta medica 83 (03/04), 261-267 , 2017 |
2017 |
| 2-Arachidonoylglycerol reduces proteoglycans and enhances remyelination in a progressive model of demyelination |
Journal of Neuroscience 37 (35), 8385-8398 , 2017 |
2017 |
| Fluorescent Probes in Medicinal Chemistry |
|
2017 |
| 2AG reduces the expression of CSPGs in astrocytes and promotes remyelination in a viral model of multiple sclerosis |
GLIA 65, E223-E223 , 2017 |
2017 |
| Ligand chain length drives activation of lipid G protein-coupled receptors |
Scientific reports 7 (1), 2020 , 2017 |
2017 |
| Development of a Nucleotide Exchange Inhibitor That Impairs Ras Oncogenic Signaling |
Chemistry - A European Journal 23 (7), 1676-1685 , 2017 |
2017 |
| Chemical probes for the study of the endogenous cannabinoid system |
Universidad Complutense de Madrid , 2016 |
2016 |
| A double-blind, randomized, cross-over, placebo-controlled, pilot trial with Sativex in Huntington’s disease |
Journal of neurology 263, 1390-1400 , 2016 |
2016 |
| Chemoproteomic Approach to Explore the Target Profile of GPCR ligands: Application to 5‐HT 1A and 5‐HT 6 Receptors |
Chemistry–A European Journal 22 (4), 1313-1321 , 2016 |
2016 |
| Endocannabinoids drive the acquisition of an alternative phenotype in microglia |
Brain, behavior, and immunity 49, 233-245 , 2015 |
2015 |
| The status of the lysophosphatidic acid receptor type 1 (LPA 1 R) |
MedChemComm 6 (1), 13-23 , 2015 |
2015 |
| A basal tone of 2-arachidonoylglycerol contributes to early oligodendrocyte progenitor proliferation by activating phosphatidylinositol 3-kinase (PI3K)/AKT and the mammalian … |
Journal of Neuroimmune Pharmacology 10, 309-317 , 2015 |
2015 |
| New inhibitors of angiogenesis with antitumor activity in vivo |
Journal of medicinal chemistry 58 (9), 3757-3766 , 2015 |
2015 |
| Role of Cannabinoid Receptor CB 2 in HER2 Pro-oncogenic Signaling in Breast Cancer |
Journal of the National Cancer Institute 107 (6), djv077 , 2015 |
2015 |
| New players for the alternative activation of microglia: Beyond Arginase-1 |
Journal of Neuroimmunology 275 (1), 164 , 2014 |
2014 |
| A reversible and selective inhibitor of monoacylglycerol lipase ameliorates multiple sclerosis |
Angewandte Chemie 126 (50), 13985-13990 , 2014 |
2014 |
| Innentitelbild: A Reversible and Selective Inhibitor of Monoacylglycerol Lipase Ameliorates Multiple Sclerosis (Angew. Chem. 50/2014) |
Angewandte Chemie 50 (126), 13842-13842 , 2014 |
2014 |
| Development of Ligands for the Validation of the Lysophosphatidic Acid Receptor LPA1 |
Universidad Complutense de Madrid , 2014 |
2014 |
| Inside Cover: A Reversible and Selective Inhibitor of Monoacylglycerol Lipase Ameliorates Multiple Sclerosis (Angew. Chem. Int. Ed. 50/2014) |
Angewandte Chemie International Edition 50 (53), 13624-13624 , 2014 |
2014 |
| The expression of cannabinoid receptor 1 is significantly increased in atopic patients |
Journal of Allergy and Clinical Immunology 133 (3), 926-929. e2 , 2014 |
2014 |
| The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system |
International Journal of Neuropsychopharmacology 16 (6), 1407-1419 , 2013 |
2013 |
| Mitochondrial CB1 receptors regulate neuronal energy metabolism |
JOURNAL OF NEUROSCIENCE RESEARCH 91 (8), 1097-1097 , 2013 |
2013 |
| Avances en el estudio de receptores acoplados a proteínas G. |
Anales de Química de la RSEQ 109 (4), 276-276 , 2013 |
2013 |
| Chemical probes for the recognition of cannabinoid receptors in native systems |
Angewandte Chemie International Edition 51 (28), 6896-6899 , 2012 |
2012 |
| Early endogenous activation of CB1 and CB2 receptors after spinal cord injury is a protective response involved in spontaneous recovery |
PLOS one 7 (11), e49057 , 2012 |
2012 |
| New synthetic inhibitors of fatty acid synthase with anticancer activity |
Journal of medicinal chemistry 55 (11), 5013-5023 , 2012 |
2012 |
| Structure–activity relationship of a new Series of reversible dual monoacylglycerol lipase/fatty acid amide hydrolase inhibitors |
Journal of Medicinal Chemistry 55 (2), 824-836 , 2012 |
2012 |
| Mitochondrial CB 1 receptors regulate neuronal energy metabolism |
Nature neuroscience 15 (4), 558-564 , 2012 |
2012 |
| Development of endocannabinoid-based chemical probes for the study of cannabinoid receptors |
Journal of medicinal chemistry 54 (14), 5265-5269 , 2011 |
2011 |
| Development of non-peptide ligands of growth factor receptor-bound protein 2-SRC homology 2 domain using molecular modeling and NMR spectroscopy |
Journal of medicinal chemistry 54 (4), 1096-1100 , 2011 |
2011 |
| Dual inhibition of α/β-hydrolase domain 6 and fatty acid amide hydrolase increases endocannabinoid levels in neurons |
Journal of Biological Chemistry 286 (33), 28723-28728 , 2011 |
2011 |
| A novel inhibitor of fatty acid synthase shows activity against HER2+ breast cancer xenografts and is active in anti-HER2 drug-resistant cell lines |
Breast Cancer Research, 2011, vol. 13, núm. 6, R131 , 2011 |
2011 |
| A novel inhibitor of fatty acid synthase shows activity against HER2+ breast cancer xenografts and is active in anti-HER2 drug-resistant cell lines |
Breast Cancer Research 13, 1-13 , 2011 |
2011 |
| Development of Molecular Probes for the Human 5-HT 6 Receptor |
Journal of medicinal chemistry 53 (19), 7095-7106 , 2010 |
2010 |
| Novel Polyhydroxylated Compounds as Fatty Acid Synthase (FASN) Inhibitors |
US Patent App. 12/665,846 , 2010 |
2010 |
| Development of Fluorescent Ligands for the Human 5-HT 1A Receptor |
ACS Medicinal Chemistry Letters 1 (6), 249-253 , 2010 |
2010 |
| L. 04: DEVELOPMENT OF CHEMICAL PROBES FOR THE STUDY OF THE CB, AND CB, CANNABINOID RECEPTORS |
Drugs of the Future 35, 7 , 2010 |
2010 |
| The constitutive production of the endocannabinoid 2‐arachidonoylglycerol participates in oligodendrocyte differentiation |
Glia 58 (16), 1913-1927 , 2010 |
2010 |
| MG28, a novel fatty acid synthase inhibitor, overcomes resistance to anti-HER therapies in breast cancer. |
Cancer Research 69 (2_Supplement), 2143 , 2009 |
2009 |
| Novel inhibitors of fatty acid synthase with anticancer activity |
Clinical Cancer Research 15 (24), 7608-7615 , 2009 |
2009 |
| DEVELOPMENT OF MONOACYLGLYCEROL LIPASE (MGL) INHIBITORS |
DRUGS OF THE FUTURE 34, 214-214 , 2009 |
2009 |
| In Vivo and In Vitro Evidence of Antitumor Activity of UCM-Gi028 [Novel FASN Inhibitor] Against Trastuzumab-Resistant Breast Cancer. |
Cancer Research 69 (24_Supplement), 5079-5079 , 2009 |
2009 |
| FROM RATIONAL LIGAND DESIGN TO TARGET VALIDATION: DEVELOPMENT OF CHEMICAL PROBES FOR THE CNS |
Drugs of the Future 34, 26-27 , 2009 |
2009 |
| NOVEL INHIBITORS OF FATTY ACID SYNTHASE (FASN) WITH ANTICANCER ACTIVITY |
DRUGS OF THE FUTURE 34, 196-196 , 2009 |
2009 |
| Translational study: a novel fatty acid synthase inhibitor, overcomes resistance to anti-HER therapies in breast cancer |
New Biotechnology, S44 , 2009 |
2009 |
| Targeted disruption of the PME-1 gene causes loss of demethylated PP2A and perinatal lethality in mice |
PloS one 3 (7), e2486 , 2008 |
2008 |
| Novel poliphenolic inhibitors of fatty acid synthase (FASN) have potential as anticancer agents |
Cancer Research 68 (9_Supplement), 5668-5668 , 2008 |
2008 |
| The medicinal chemistry of agents targeting monoacylglycerol lipase |
Current Topics in Medicinal Chemistry 8 (3), 231-246 , 2008 |
2008 |
| WIN 55,212-2 downregulates VCAM-1 in a viral model of multiple sclerosis |
MULTIPLE SCLEROSIS 14, S235-S235 , 2008 |
2008 |
| Neurochemical effects of the endocannabinoid uptake inhibitor UCM707 in various rat brain regions |
Life sciences 80 (10), 979-988 , 2007 |
2007 |
| Structure− Activity Relationship of a Series of Inhibitors of Monoacylglycerol Hydrolysis Comparison with Effects upon Fatty Acid Amide Hydrolase |
Journal of medicinal chemistry 50 (20), 5012-5023 , 2007 |
2007 |
| El sistema cannabinoide en situaciones de neuroinflamación: perspectivas terapéuticas en la esclerosis múltiple |
Viguera Editores , 2006 |
2006 |
| Number 1—January 2006 |
European Neuropsychopharmacology 16, 643-648 , 2006 |
2006 |
| UCM707, an inhibitor of the anandamide uptake, behaves as a symptom control agent in models of Huntington's disease and multiple sclerosis, but fails to delay/arrest the … |
European neuropsychopharmacology 16 (1), 7-18 , 2006 |
2006 |
| CYP3A, 178 |
European Neuropsychopharmacology 16, 625-629 , 2006 |
2006 |
| Cannabinoid system and neuroinflammation: therapeutic perspectives in multiple sclerosis |
Viguera Editores , 2006 |
2006 |
| Therapeutic perspectives of inhibitors of endocannabinoid degradation |
Current Drug Targets-CNS & Neurological Disorders 4 (6), 697-707 , 2005 |
2005 |
| CB1 and CB2 cannabinoid receptor binding studies based on modeling and mutagenesis approaches |
Mini reviews in medicinal chemistry 5 (7), 651-658 , 2005 |
2005 |
| Estudio del proceso de recaptación de anandamida mediante la síntesis de inhibidores y evaluación de su aplicabilidad terapéutica |
Universidad Complutense de Madrid, Servicio de Publicaciones , 2005 |
2005 |
| Effect of repeated systemic administration of selective inhibitors of endocannabinoid inactivation on rat brain endocannabinoid levels |
Biochemical pharmacology 70 (3), 446-452 , 2005 |
2005 |
| Effect of anandamide uptake inhibition in the production of nitric oxide and in the release of cytokines in astrocyte cultures |
Glia 52 (2), 163-168 , 2005 |
2005 |
| Involvement of cannabinoids in cellular proliferation |
Mini reviews in medicinal chemistry 5 (1), 97-106 , 2005 |
2005 |
| Activation of the endocannabinoid system as a therapeutic approach in a murine model of multiple sclerosis |
The FASEB journal 19 (10), 1338-1340 , 2005 |
2005 |
| Characterization of an anandamide degradation system in prostate epithelial PC‐3 cells: synthesis of new transporter inhibitors as tools for this study |
British journal of pharmacology 141 (3), 457-467 , 2004 |
2004 |
| Characterization of an anandamide degradation system in prostate epithelial PC-3 cells: Synthesis of new... |
British Journal of Pharmacology 141, 457-467 , 2004 |
2004 |
| Comparison of anandamide transport in FAAH wild-type and knockout neurons: evidence for contributions by both FAAH and the CB1 receptor to anandamide uptake |
Biochemistry 43 (25), 8184-8190 , 2004 |
2004 |
| The anandamide degradation system as potential target for the treatment of central nervous system related disorders |
Current Medicinal Chemistry-Central Nervous System Agents 4 (3), 155-160 , 2004 |
2004 |
| Inhibition of fatty acid amidohydrolase, the enzyme responsible for the metabolism of the endocannabinoid anandamide, by analogues of arachidonoyl-serotonin |
Journal of enzyme inhibition and medicinal chemistry 18 (3), 225-231 , 2003 |
2003 |
| van der, Lopez-Rodriguez ML, Casanova E, Schutz G, Zieglgansberger W, Di Marzo V, Behl C, Lutz B: CB1 cannabinoid receptors and on-demand defense against excitotoxicity |
Science 302, 84-88 , 2003 |
2003 |
| Design, synthesis and biological evaluation of new endocannabinoid transporter inhibitors |
European journal of medicinal chemistry 38 (4), 403-412 , 2003 |
2003 |
| CB1 cannabinoid receptors and on-demand defense against excitotoxicity |
Science 302 (5642), 84-88 , 2003 |
2003 |
| VR1 receptor modulators as potential drugs for neuropathic pain |
Mini Reviews in Medicinal Chemistry 3 (7), 729-748 , 2003 |
2003 |
| Design, synthesis, and biological evaluation of new inhibitors of the endocannabinoid uptake: comparison with effects on fatty acid amidohydrolase |
Journal of medicinal chemistry 46 (8), 1512-1522 , 2003 |
2003 |
| UCM707, a potent and selective inhibitor of endocannabinoid uptake, potentiates hypokinetic and antinociceptive effects of anandamide |
European journal of pharmacology 449 (1-2), 99-103 , 2002 |
2002 |
| Endocannabinoid transporter inhibitors |
Current Medicinal Chemistry-Central Nervous System Agents 2 (2), 129-141 , 2002 |
2002 |
| Nuevas tendencias en la utilidad terapeútica de los cannabinoides |
Anales de Química de la RSEQ, 14-21 , 2001 |
2001 |
| Design, synthesis and biological evaluation of novel arachidonic acid derivatives as highly potent and selective endocannabinoid transporter inhibitors |
Journal of medicinal chemistry 44 (26), 4505-4508 , 2001 |
2001 |
