Publicaciones Google Scholar de
1980 a
2022
| Título |
Fuente |
Fecha |
| P2X7 receptor blockade reduces tau induced toxicity, therapeutic implications in tauopathies |
Progress in Neurobiology 208, 102173 , 2022 |
2022 |
| TNAP upregulation is a critical factor in Tauopathies and its blockade ameliorates neurotoxicity and increases life-expectancy |
Neurobiology of Disease 165, 105632 , 2022 |
2022 |
| Aprendizaje basado en proyectos y aula invertida de la asignatura de Bioquímica del grado de Veterinaria: elaboración de nuevo material docente y empleo de la red social … |
|
2021 |
| P2X7 as common therapeutic target in brain diseases |
Frontiers in Molecular Neuroscience 14, 656011 , 2021 |
2021 |
| Tissue-nonspecific Alkaline Phosphatase Blockade Ameliorates Behavioural Deficits and Life-expectancy on Tauopathies |
|
2020 |
| ATP Measurement in Cerebrospinal Fluid Using a Microplate Reader |
Purinergic Signaling, 233-241 , 2020 |
2020 |
| The role of P2X7 receptor in Alzheimer’s disease |
Frontiers in Molecular Neuroscience 13, 94 , 2020 |
2020 |
| Amyloid peptide induced neuroinflammation increases the P2X7 receptor expression in microglial cells, impacting on its functionality |
Frontiers in cellular neuroscience 13, 143 , 2019 |
2019 |
| Nucleotides regulate the common molecular mechanisms that underlie neurodegenerative diseases; therapeutic implications |
Brain Research Bulletin 151, 84-91 , 2019 |
2019 |
| Peripheral nervous system effects in the PS19 tau transgenic mouse model of tauopathy |
Neuroscience Letters 698, 204-208 , 2019 |
2019 |
| MicroRNA-22 controls aberrant neurogenesis and changes in neuronal morphology after status epilepticus |
Frontiers in molecular neuroscience, 442 , 2018 |
2018 |
| Haploinsufficient TNAP mice display decreased extracellular ATP levels and expression of pannexin-1 channels |
Frontiers in pharmacology 9, 170 , 2018 |
2018 |
| Regulation of the celular proteostasis by the purinergic signaling. Relevance in neurological disorders |
PURINERGIC SIGNALLING 14, S16-S16 , 2018 |
2018 |
| The regulation of proteostasis in glial cells by nucleotide receptors is key in acute neuroinflammation |
The FASEB Journal 32 (6), 3020-3032 , 2018 |
2018 |
| The neurotoxic role of extracellular tau protein |
International journal of molecular sciences 19 (4), 998 , 2018 |
2018 |
| TNAP stimulates vascular smooth muscle cell trans-differentiation into chondrocytes through calcium deposition and BMP-2 activation: Possible implication in atherosclerotic … |
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (3), 643-653 , 2017 |
2017 |
| Expression and function of the metabotropic purinergic P2Y receptor family in experimental seizure models and patients with drug‐refractory epilepsy |
Epilepsia 58 (9), 1603-1614 , 2017 |
2017 |
| Regulation of proteasome activity by P2Y2 receptor underlies the neuroprotective effects of extracellular nucleotides |
Elsevier , 2017 |
2017 |
| Neuronal P2X7 receptor: involvement in neuronal physiology and pathology |
Journal of Neuroscience 37 (30), 7063-7072 , 2017 |
2017 |
| Regulation of proteasome activity by P2Y2 receptor underlies the neuroprotective effects of extracellular nucleotides |
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (1), 43-51 , 2017 |
2017 |
| Presynaptic P2X1-3 and α3-containing nicotinic receptors assemble into functionally interacting ion channels in the rat hippocampus |
Neuropharmacology 105, 241-257 , 2016 |
2016 |
| Transient P2X7 receptor antagonism produces lasting reductions in spontaneous seizures and gliosis in experimental temporal lobe epilepsy |
Journal of Neuroscience 36 (22), 5920-5932 , 2016 |
2016 |
| Neurodevelopmental alterations and seizures developed by mouse model of infantile hypophosphatasia are associated with purinergic signalling deregulation |
Human Molecular Genetics 25 (19), 4143-4156 , 2016 |
2016 |
| Age-related nuclear translocation of P2X6 subunit modifies splicing activity interacting with splicing factor 3A1 |
PloS one 10 (4), e0123121 , 2015 |
2015 |
| Diadenosine tetraphosphate contributes to carbachol-induced tear secretion |
Purinergic signalling 11 (1), 87-93 , 2015 |
2015 |
| Tissue-nonspecific alkaline phosphatase regulates purinergic transmission in the central nervous system during development and disease |
Computational and structural biotechnology journal 13, 95-100 , 2015 |
2015 |
| TNAP plays a key role in neural differentiation as well as in neurodegenerative disorders |
Neuronal Tissue-Nonspecific Alkaline Phosphatase (TNAP), 375-385 , 2015 |
2015 |
| microRNA targeting of the P2X7 purinoceptor opposes a contralateral epileptogenic focus in the hippocampus |
Scientific reports 5 (1), 1-17 , 2015 |
2015 |
| Role of P2X7 and P2Y2 receptors on α-secretase-dependent APP processing: Control of amyloid plaques formation “in vivo” by P2X7 receptor |
Computational and structural biotechnology journal 13, 176-181 , 2015 |
2015 |
| Sources of extracellular tau and its signaling |
Journal of Alzheimer's Disease 40 (s1), S7-S15 , 2014 |
2014 |
| Tau triggers tear secretion by interacting with muscarinic acetylcholine receptors in New Zealand white rabbits |
Journal of Alzheimer's Disease 40 (s1), S71-S77 , 2014 |
2014 |
| Sp1 mediates transcriptional regulation of P2X7 receptors in the nervous system: implications in neural cell differentiation |
PURINERGIC SIGNALLING 10 (4), 844-844 , 2014 |
2014 |
| Nuclear location of P2X6 subunit in mouse hippocampal neurons |
PURINERGIC SIGNALLING 10 (4), 837-837 , 2014 |
2014 |
| Regulatory mechanisms and functional significance of P2X7R in epilepsy |
PURINERGIC SIGNALLING 10 (4), 724-724 , 2014 |
2014 |
| TNAP controls the neuronal differentiation through regulating P2X receptors presents on axonal growth cone. Involvement on neurodegenerative disorder |
PURINERGIC SIGNALLING 10 (4), 715-715 , 2014 |
2014 |
| The regulation and function of the ATP-gated P2X7 receptor in epilepsy |
PURINERGIC SIGNALLING 10 (4), 839-839 , 2014 |
2014 |
| P2X7 receptor inhibition interrupts the progression of seizures in immature rats and reduces hippocampal damage |
CNS neuroscience & therapeutics 20 (6), 556-564 , 2014 |
2014 |
| TAU TRANSPORT FROM CELL TO CELL |
Alzheimer's & Dementia 10, P161-P161 , 2014 |
2014 |
| P2X receptors as targets for the treatment of status epilepticus |
Frontiers in cellular neuroscience 7, 237 , 2013 |
2013 |
| Increased neocortical expression of the P 2X7 receptor after status epilepticus and anticonvulsant effect of P 2X7 receptor antagonist A‐438079 |
Epilepsia 54 (9), 1551-1561 , 2013 |
2013 |
| The specificity protein factor Sp1 mediates transcriptional regulation of P2X7 receptors in the nervous system |
Journal of Biological Chemistry 287 (53), 44628-44644 , 2012 |
2012 |
| Adenylate cyclase 5 coordinates the action of ADP, P2Y1, P2Y13 and ATP-gated P2X7 receptors on axonal elongation |
Journal of cell science 125 (1), 176-188 , 2012 |
2012 |
| α-Synuclein accumulates in huntingtin inclusions but forms independent filaments and its deficiency attenuates early phenotype in a mouse model of Huntington's disease |
Human molecular genetics 21 (3), 495-510 , 2012 |
2012 |
| P2X7 receptor in epilepsy; role in pathophysiology and potential targeting for seizure control |
International journal of physiology, pathophysiology and pharmacology 4 (4), 174 , 2012 |
2012 |
| Looking for novel functions of tau |
Biochemical Society Transactions 40 (4), 653-655 , 2012 |
2012 |
| Seizure suppression and neuroprotection by targeting the purinergic P2X7 receptor during status epilepticus in mice |
The FASEB journal 26 (4), 1616-1628 , 2012 |
2012 |
| Tau overexpression results in its secretion via membrane vesicles |
Neurodegenerative diseases 10 (1-4), 73-75 , 2012 |
2012 |
| In vivo P2X7 inhibition reduces amyloid plaques in Alzheimer's disease through GSK3β and secretases |
Neurobiology of aging 33 (8), 1816-1828 , 2012 |
2012 |
| Opposite effects of P2X7 and P2Y2 nucleotide receptors on α-secretase-dependent APP processing in Neuro-2a cells |
FEBS letters 585 (14), 2255-2262 , 2011 |
2011 |
| Tissue-nonspecific alkaline phosphatase promotes axonal growth of hippocampal neurons |
Molecular biology of the cell 22 (7), 1014-1024 , 2011 |
2011 |
| PROGRAMA DEL PRIMER SEMINARIO DE INVESTIGACIÓN DEL IdISSC |
Psychiatry Res , 2011 |
2011 |
| Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington’s disease |
Brain 134 (1), 119-136 , 2011 |
2011 |
| Tissue-nonspecific alkaline phosphatase promotes the neurotoxicity effect of extracellular tau |
Journal of Biological Chemistry 285 (42), 32539-32548 , 2010 |
2010 |
| Uso de compuestos que se unen al dominio de unión a microtúbulos de tau en la elaboración de composiciones farmacéuticas, dichas composiciones farmacéuticas y su aplicación en … |
|
2010 |
| PH domain leucine-rich repeat protein phosphatase 1 contributes to maintain the activation of the PI3K/Akt pro-survival pathway in Huntington's disease striatum |
Cell Death & Differentiation 17 (2), 324-335 , 2010 |
2010 |
| Acute polyglutamine expression in inducible mouse model unravels ubiquitin/proteasome system impairment and permanent recovery attributable to aggregate formation |
Journal of Neuroscience 30 (10), 3675-3688 , 2010 |
2010 |
| Use of P2X7 receptor antagonists to promote axonal growth and ramification |
|
2010 |
| Ca 2+ /calmodulin‐dependent kinase II signalling cascade mediates P2X7 receptor‐dependent inhibition of neuritogenesis in neuroblastoma cells |
The FEBS journal 276 (18), 5307-5325 , 2009 |
2009 |
| Reduced calcineurin protein levels and activity in exon-1 mouse models of Huntington's disease: role in excitotoxicity |
Neurobiology of disease 36 (3), 461-469 , 2009 |
2009 |
| Disturbances of VMAT2 and P2Y2 Expression in the Retina of a Mouse Model of Huntington Disease |
Investigative Ophthalmology & Visual Science 50 (13), 4142-4142 , 2009 |
2009 |
| Mecanismos implicados en la axonogénesis, el crecimiento axonal y la localización de proteínas en el axón |
Monografías de la Real Academia Nacional de Farmacia , 2009 |
2009 |
| ATP (P2X1-3) AND alpha 3 beta 2 NICOTINIC ACETYLCHOLINE RECEPTORS INTERACT PHYSICALLY AND FUNCTIONALLY IN HIPPOCAMPAL TERMINALS |
JOURNAL OF PHYSIOLOGICAL SCIENCES 59, 74-74 , 2009 |
2009 |
| Characteristics and consequences of muscarinic receptor activation by tau protein |
European Neuropsychopharmacology 19 (10), 708-717 , 2009 |
2009 |
| Accumulation of ubiquitin conjugates in a polyglutamine disease model occurs without global ubiquitin/proteasome system impairment |
Proceedings of the National Academy of Sciences 106 (33), 13986-13991 , 2009 |
2009 |
| Altered P2X7‐receptor level and function in mouse models of Huntington's disease and therapeutic efficacy of antagonist administration |
The FASEB Journal 23 (6), 1893-1906 , 2009 |
2009 |
| Method for the in vitro diagnosis/prognosis of Huntington's chorea |
|
2008 |
| Inhibition of the ATP-gated P2X7 receptor promotes axonal growth and branching in cultured hippocampal neurons |
Journal of cell science 121 (22), 3717-3728 , 2008 |
2008 |
| Extracellular tau promotes intracellular calcium increase through M1 and M3 muscarinic receptors in neuronal cells |
Molecular and Cellular Neuroscience 37 (4), 673-681 , 2008 |
2008 |
| Is the ubiquitin-proteasome system impaired in Huntington’s disease? |
Cellular and Molecular Life Sciences 64 (17), 2245-2257 , 2007 |
2007 |
| Papel fisiológico de los nucleótidos extracelulares en el sistema nervioso central: señalización vía receptores P2X y P2Y |
Anales de la Real Academia Nacional de Farmacia, 1127-1158 , 2007 |
2007 |
| Testing the possible inhibition of proteasome by direct interaction with ubiquitylated and aggregated huntingtin |
Brain research bulletin 72 (2-3), 121-123 , 2007 |
2007 |
| Physiological role of extracellular nucleotides at the central nervous system: signalling through P2X and P2Y receptors |
ANALES DE LA REAL ACADEMIA NACIONAL DE FARMACIA 73 (4), 1127-1157 , 2007 |
2007 |
| Physiological role of extracellular nucleotides at the central nervous system: signalling through P2X and P2Y receptors |
An. R. Acad. Farm, 127-157 , 2007 |
2007 |
| BH3‐only proteins Bid and Bim EL are differentially involved in neuronal dysfunction in mouse models of Huntington's disease |
Journal of neuroscience research 85 (12), 2756-2769 , 2007 |
2007 |
| Extracellular tau is toxic to neuronal cells |
FEBS letters 580 (20), 4842-4850 , 2006 |
2006 |
| Role of CaCMKII in the cross talk between ionotropic nucleotide and nicotinic receptors in individual cholinergic terminals |
Journal of Molecular Neuroscience 30 (1-2), 177-180 , 2006 |
2006 |
| Reduced expression of the TrkB receptor in Huntington's disease mouse models and in human brain |
European Journal of Neuroscience 23 (3), 649-658 , 2006 |
2006 |
| The Ups in Neurodegenerative Diseases and Aging Huntington’s Disease |
The Proteasome in Neurodegeneration, 225-235 , 2006 |
2006 |
| Inhibition of 26S proteasome activity by huntingtin filaments but not inclusion bodies isolated from mouse and human brain |
Journal of neurochemistry 98 (5), 1585-1596 , 2006 |
2006 |
| The ubiquitin-proteasome system in Huntington’s disease |
The Neuroscientist 11 (6), 583-594 , 2005 |
2005 |
| Full motor recovery despite striatal neuron loss and formation of irreversible amyloid-like inclusions in a conditional mouse model of Huntington's disease |
Journal of Neuroscience 25 (42), 9773-9781 , 2005 |
2005 |
| Testing the ubiquitin-proteasome hypothesis of neurodegeneration in vivo |
Trends in neurosciences 27 (2), 66-69 , 2004 |
2004 |
| Enhaced induction of the immunoproteasome by interferon gamma in neurons expressing mutant huntingtin |
Neurotoxicity research 6 (6), 463-468 , 2004 |
2004 |
| Regulation of presynaptic ionotropic nucleotide receptors |
FUNDAMENTAL & CLINICAL PHARMACOLOGY 18, 13-13 , 2004 |
2004 |
| Biochemical, ultrastructural, and reversibility studies on huntingtin filaments isolated from mouse and human brain |
Journal of Neuroscience 24 (42), 9361-9371 , 2004 |
2004 |
| Presence of functional ATP and dinucleotide receptors in glutamatergic synaptic terminals from rat midbrain |
Journal of neurochemistry 87 (1), 160-171 , 2003 |
2003 |
| P2X7 receptors in rat brain: presence in synaptic terminals and granule cells |
Neurochemical research 28 (10), 1597-1605 , 2003 |
2003 |
| Neuronal induction of the immunoproteasome in Huntington's disease |
Journal of Neuroscience 23 (37), 11653-11661 , 2003 |
2003 |
| Co-localisation of functional nicotinic and ionotropic nucleotide receptors in isolated cholinergic synaptic terminals |
Neuropharmacology 42 (1), 20-33 , 2002 |
2002 |
| Modulación de la neurotransmisión mediada por nucleótidos y dinucleótidos de adenina a nivel presináptico |
Universidad Complutense de Madrid , 2002 |
2002 |
| Cloning and characterization of two novel zebrafish P2X receptor subunits |
Biochemical and biophysical research communications 295 (4), 849-853 , 2002 |
2002 |
| Modulation of the rat hippocampal dinucleotide receptor by adenosine receptor activation |
Journal of Pharmacology and Experimental Therapeutics 301 (2), 441-450 , 2002 |
2002 |
| Presence of different ATP receptors on rat midbrain single synaptic terminals. Involvement of the P2X3 subunits |
Neuroscience letters 301 (3), 159-162 , 2001 |
2001 |
| Adenosine triphosphate and diadenosine pentaphosphate induce [Ca 2+ ] i increase in rat basal ganglia aminergic terminals |
Journal of Neuroscience Research 64 (2), 174-182 , 2001 |
2001 |
| Presynaptic diadenosine polyphosphate receptors: interaction with other neurotransmitter systems |
Drug development research 52 (1-2), 239-248 , 2001 |
2001 |
| Interaction between cholinergic and purinergic system |
JOURNAL OF NEUROCHEMISTRY 78, 151-151 , 2001 |
2001 |
| Independent receptors for diadenosine pentaphosphate and ATP in rat midbrain single synaptic terminals |
European Journal of Neuroscience 14 (6), 918-926 , 2001 |
2001 |
| Receptores nicotínicos neurales: interacción con receptores purinérgicos |
Anales de la Real Academia Nacional de Farmacia 66 (2) , 2000 |
2000 |
| Presynaptic signalling mediated by mono-and dinucleotides in the central nervous system |
Journal of the autonomic nervous system 81 (1-3), 195-199 , 2000 |
2000 |
| Diadenosine polyphosphates facilitate the evoked release of acetylcholine from rat hippocampal nerve terminals |
Brain research 879 (1), 50-54 , 2000 |
2000 |
| Diadenosine polyphosphate receptors: from rat and guinea-pig brain to human nervous system |
Pharmacology & therapeutics 87 (2-3), 103-115 , 2000 |
2000 |
| Modulation of the dinucleotide receptor present in rat midbrain synaptosomes by adenosine and ATP |
British journal of pharmacology 130 (2), 434-440 , 2000 |
2000 |
| Nicotine is a volatile alkaloid that interacts with the ionotropic acetylcholine receptors, thus named nicotinic receptors |
Anales de la Real Academia Nacional de Farmacia, 1 , 2000 |
2000 |
| Diadenosine polyphosphates, extracellular function |
Nucleotides and their Receptors in the Nervous System, 397 , 1999 |
1999 |
| Presence of dinucleotide and ATP receptors in human cerebrocortical synaptic terminals |
European journal of pharmacology 366 (2-3), 159-165 , 1999 |
1999 |
| Diadenosine polyphosphates, extracellular function and catabolism |
Progress in brain research 120, 397-409 , 1999 |
1999 |
